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Scientific Oral Presentations

Sleep Medicine

Session: Scientific Oral Presentations 1 - Sleep Medicine

Impact of Postoperative Weight Changes on Upper Airway Stimulation Success for Obstructive Sleep Apnea

Saturday, September 28, 2024
4:30 PM – 4:36 PM EDT
Location: MBCC, 238-239
Disclosure(s):
Praneet Chandra Kaki, BS:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Jennifer A. Goldfarb, MHS:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Nicole Louise Molin, MD:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Colin T. Huntley, MD:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Maurits S. Boon, MD:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Introduction: Obesity is a well-established risk factor for obstructive sleep apnea (OSA), and weight loss is often recommended in conjunction with upper airway stimulation (UAS) to manage OSA in CPAP-intolerant patients. Our study assesses how long-term changes in body mass index (BMI) following UAS correlate with surgical success.

Methods: We performed a retrospective cohort study of OSA patients who underwent UAS at our institution from 2017-2022. Patients were included if they had pre and postoperative sleep studies and BMI data one year following surgery. Patients were stratified into three cohorts based on their BMI change from baseline to one year following surgery: 1) remaining within 2 BMI points, 2) gaining at least 2 BMI points, or 3) losing at least 2 BMI points. One-way ANOVA and chi-squared tests were performed for the analysis using R Studio.

Results: Following UAS, there was a significant reduction (p < 0.001) in post-operative AHI (19.23 ± 16.92 events/hour) compared to preoperative AHI (33.60 ± 17.29). Patients, who maintained a stable BMI after UAS, showed a greater reduction in AHI compared to patients who gained 2+ BMI points (-15.41 ± 20.23 vs -1.59 ± 26.85, p < 0.02). Patients who lost 2+ BMI points following UAS showed the greatest reduction in AHI compared to those with stable BMI and those who gained 2+ BMI points (-24.23 ± 15.53 vs -15.41 ± 20.23 vs -1.59 ± 26.85, p < 0.001). There were, however, no significant differences in the changes in Epworth Sleepiness Scale scores or rates of surgical success per Sher15 response criteria.

Conclusions: While UAS effectively reduces AHI, this effect was found to be most significant in patients who experience weight loss compared to those who gain or remain in stable body weight. Our study underscores the importance of post-operative weight management and its adjunctive role in improving UAS surgical success in OSA patients.

    Presenting Author(s)

  • Praneet C. Kaki, BS

    Medical Student
    Sidney Kimmel Medical College, Thomas Jefferson University
    Kendall Park, New Jersey, United States

    Disclosure(s):

    faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

    • Co-Author(s)

  • Chihun J. Han, MD

    Sleep Medicine/Surgery Fellow
    UPMC
    Philadelphia, PA, United States

    Disclosure information not submitted.

  • Jennifer A. Goldfarb, MHS

    Medical Student
    Sidney Kimmel Medical College, Thomas Jefferson University
    Philadelphia, PA, United States

    Disclosure(s):

    faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

  • Nicole L. Molin, MD

    Physician
    ENT consultants of Nevada
    Las Vegas, Nevada, United States

    Disclosure(s):

    faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

  • Colin T. Huntley, MD

    Associate Professor
    Thomas Jefferson University Hospital - Department of Otolaryngology
    Philadelphia, Pennsylvania, United States

    Disclosure(s):

    faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

  • MB

    Maurits S. Boon, MD

    Professor
    Thomas Jefferson University Hospital - Department of Otolaryngology
    Philadelphia, PA, United States

    Disclosure(s):

    faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

    • Senior Author(s)

  • Colin T. Huntley, MD

    Associate Professor
    Thomas Jefferson University Hospital - Department of Otolaryngology
    Philadelphia, Pennsylvania, United States

    Disclosure(s):

    faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.