(1224) Posterior Nasal Nerve Neurectomy for the Treatment of Chronic Rhinosinusitis With Nasal Polyposis

Introduction: Managing chronic rhinosinusitis with nasal polyposis (CRSsNP) is always challenging due to the chronicity of the disease and its intractable course. Posterior nasal neurectomy can be effective in alleviating symptoms of CRSsNP.

Methods: The study was conducted in a tertiary care referral hospital from August 2019 to April 2022. A total of 46 patients of CRSsNP were included (23 patients in the study and 23 in the control group). Patients in the study group underwent endoscopic sinus surgery (ESS) and PNN and patients in the control group with ESS. The symptoms and quality of life improvement were assessed at 1,4,12, and 24 weeks after the surgery.

Results: On intragroup analysis between the preoperative and postoperative scores (SNOT-22, RSDI, and LK Score), we found a significant difference for each (p < 0.05). When the improvement of outcome scores was compared between the two groups, a significant difference was obtained for SNOT-22 and RSDI scores at one week and four weeks (p < 0.05). There was no difference found for the duration of surgery/complications (p = 1).

Conclusions: The PNN can be an effective add-on procedure in patients with CRSwNP in alleviating short-term control of the symptoms and the quality of life. A larger sample size with long-term follow-up may be required for a better understanding of the efficacy of the PNN in patients with CRSwNP.