(0813) Efficacy of Combined Treatment of KTP Laser and Steroid Injection in Patients With Reinke's Edema
Monday, September 30, 2024
12:00 PM – 1:00 PM EDT
Disclosure(s):
Jung-Hae Cho: No relevant relationships to disclose.
Introduction: Despite numerous management approaches proposed, there is no clearly superior method for treating Reinke's edema. We aimed to assess the efficacy and safety of combined treatment using 532 nm pulsed Potassium-Titanyl-Phosphate (KTP) laser and vocal fold steroid injection following excision in patients with Reinke's edema.
Methods: Between 2018 and 2023, 58 consecutive patients with Reinke's edema underwent either excision using microflap technique (Group 1) or combination therapy involving KTP laser ablation and vocal fold steroid injection (Group 2). Voice quality and outcome were evaluated using the multi-dimensional voice program (MVP) phonatory aerodynamic system before and after surgery. Subjective changes were assessed using the GRBAS scale, Voice Handicap Index (VHI), and videostroboscopy. The changes in voice profiles after treatment were compared between the 2 groups.
Results: The mean age of the patients was 58.4 years, with 28 patients in Group 1 and 30 patients in Group 2. At an average postoperative follow-up of 14.2 weeks (range 10–68), overall postoperative voice parameters significantly improved in both groups. Videostroboscopic examination revealed a lower rate of recurrent lesions in Group 2 (combination treatment) compared to Group 1 (microflap excision). No recurrence was observed in the combination treatment group. Postoperative voice profiles, including VHI, GRBAS score, and maximum phonation time, demonstrated significant improvements in Group 2 compared to Group 1.
Conclusions: Treatment of Reinke's edema using a combination of 532 nm KTP laser and vocal fold steroid injection following excision with microflap technique shows promise. Further prospective randomized controlled studies are warranted to confirm its efficacy.