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Scientific Oral Presentations

Pediatric Otolaryngology

Session: Scientific Oral Presentations 7 - Pediatric Otolaryngology

Efficacy and Safety of Lasers in Treating Head and Neck Capillary Malformations: A Systematic Review and Meta-analysis

Tuesday, October 1, 2024
9:54 AM – 10:00 AM EDT
Location: MBCC, 244-245
Disclosure(s):
Soroush Farsi:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Gresham T. Richter, MD:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Introduction: Laser therapy has emerged as the primary treatment modality for capillary malformation (Port Wine Stain) showing promising results. This systematic review and meta-analysis aim to evaluate the comparative effectiveness and safety of frequently employed lasers in the management of capillary malformations of the head and neck.

Methods: Embase, PubMed, Cochrane, and Web of Science were comprehensively searched for articles from their inception up to August 2023 by 2 independent reviewers. The quality of the included studies was assessed using the Newcastle-Ottawa scale (NOS) criteria. In this meta-analysis, patients achieving 25-100% clearance were categorized as successful treatment, while those with 0-25% clearance were considered non-responsive to the treatment.

Results: There were 725 abstracts screened and 14 full-text articles included, comprising a total of 714 patients with a mean age of 19.5 years. The mean number of laser treatments per patient was 6.8 sessions, with 80% of patients undergoing Pulsed Dye Laser (PDL) treatment, 12% receiving Nd:YAG laser treatment, and 8% opting for 577 nm Yellow laser treatment. The pooled overall success rate was 91% (95% CI 0.96-0.983, I2 0%). Subgroup analysis for overall response showed that the pooled response rate for PDL was 90% (95% CI: 0.94-0.973; I2=0%, n=486),  99% for Nd:YAG (95% CI: 0.979-1.008; I2=0%, n=119), 86% for Yellow 577 (95% CI: 0.7621-0.964; I2=0%, n=43). Furthermore, a subgroup analysis of post-treatment complications revealed a pooled complication rate of 10% for PDL (95% CI: 0.031-0.147; I2=87.9%, n=63) and 4.2% for Nd:YAG laser (95% CI: 0.007-0.080; I2=0%, n=5).

Conclusions: Our meta-analysis reveals that laser treatment is a safe and effective procedure for managing capillary malformation in the head and neck region. Nd:YAG exhibits a higher overall treatment response and fewer post-laser complications when compared to PDL and 577 yellow laser treatments.

    Presenting Author(s)

  • Soroush Farsi

    Medical Student
    Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences
    El Paso, Texas, United States

    Disclosure(s):

    faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

    Resources

    • Senior Author(s)

  • GR

    Gresham T. Richter, MD

    Professor, Vice Chair, Chief
    UAMS
    Little Rock, AR, United States

    Disclosure(s):

    faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

    • Co-Author(s)

  • WB

    Walker Bartels

    University of Arkansas for Medical Sciences (UAMS), United States

    Disclosure information not submitted.

  • LH

    Larkin Harris

    UAMS, United States

    Disclosure information not submitted.