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Scientific Oral Presentations

Laryngology/Broncho-Esophagology

Session: Scientific Oral Presentations 2 - Laryngology/Broncho-Esophagology

Real-Time Light-Guided Vocal Fold Injection With Hyaluronic Acid for Unilateral Vocal Fold Paralysis

Sunday, September 29, 2024

10:12 AM – 10:18 AM EDT

Location: MBCC, 224

Disclosure(s):

Seo Young Kim, MD:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Jeong-Yeon Ji, MD:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Woo-Jin JEONG, MD, PhD:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Introduction: Accurate localization of the needle tip proves challenging due to its invisibility during the cricothyroid (CT) approach. To overcome this limitation, a novel technique, real-time light-guided VFI (RL-VFI), has been recently developed for injection under simultaneous light guidance in CT approach. This study aims to introduce RL-VFI with hyaluronic acid (HA) for unilateral vocal fold paralysis (UVFP).

Methods: This retrospective study included 265 patients treated with RL-VFI for unilateral VFP between September 2020 and December 2023. Adverse events were monitored during the procedure and one month postoperatively. Laryngoscopic findings, VHI-10, voice analyses were assessed both before and after RL-VFI.

Results: A total of 380 RL-VFI procedures were conducted in 265 patients in an office-based setting. VFP was primarily observed on the left side (83.7%), mainly caused by surgery (62.9%) and metastasis (23.4%). Just 2 patients with severe gag reflex were converted to VFI under general anesthesia. In 378 procedures (99.5%), HA was injected at the proper location in the paralyzed VF under light guidance. No cases were injected superficially on the free margin of VFs. There were also 2 cases of vasovagal syncope and one case of laryngeal spasm that occurred, along with one case of bleeding due to accidental cough. There were no delayed complications or unscheduled hospital visits. Pre and postoperative voice analyses were completed in 223 cases (58.5%), demonstrating significant improvements in glottic gap and voice parameters after RL-VFI.

Conclusions: This retrospective study included 265 patients treated with RL-VFI for unilateral VFP between September 2020 and December 2023. Adverse events were monitored during the procedure and one month postoperatively. Laryngoscopic findings, VHI-10, voice analyses were assessed both before and after RL-VFI.

Presenting Author(s)

Seo Young Kim, MD

Fellow
Seoul National University Bundang Hospital
Seongnam-si, Kyonggi-do, Republic of Korea

Disclosure(s):
faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Co-Author(s)

Jeong-Yeon Ji, MD

Clinical Assistant Professor
Department of Otorhinolaryngology - Head and Neck Surgery, Seoul National University Bundang Hospital
Seongnam-si, Kyonggi-do, Republic of Korea

Disclosure(s):
faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.
JK

Ji Won Kim, MD

Seoul National University Bundang Hospital, Republic of Korea

Disclosure information not submitted.
Woo-Jin Jeong, MD, PhD

Professor
Seoul National University Bundang Hospital
Seoul, Kyonggi-do, Republic of Korea

Disclosure(s):
faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Senior Author(s)

Wonjae Cha, MD, PhD

Associate Professor
Department of Otorhinolaryngology - Head and Neck Surgery, Seoul National University Bundang Hospital
Seongnam-si, Kyonggi-do, Republic of Korea

Disclosure information not submitted.